Trade union Mandate yesterday issued the retailer with formal notice of industrial action beginning on September 10 at its stores in Tallaght and Dun Laoghaire, Mullingar and Naas.
It said 88pc of the 180 Irish workers facing losing their jobs are angered that the company is insisting on compulsory redundancies only.
General secretary John Douglas said: “The result of the ballot clearly indicates the level of unity among the Marks & Spencer workers.
“We have registered our frustration and disappointment with the company, whose actions have caused great anxiety for their workers.”
Marks & Spencer Ireland boss Jonathan Glenister said the firm was “disappointed by the result” of the ballot.